Gordon Fox • October 14, 2021
Weight loss improves HCM patients’ heart health

Weight management is a challenge for many. Losing weight is a challenge for nearly everyone who tries it. It can be more difficult for many HCM patients because we often take drugs that slow us down. It’s also hard to study: researchers can assign different groups to different diets, but how can they tell who follows the diet closely, loosely, or not at all? How can they know how much exercise people really get?  This problem is more challenging because we also know that weight loss is important for many people, especially those with HCM.

A recent pilot study (20 subjects all with BMI greater than 30, which is labeled “obese”) by a group in Italy, the UK, and the US, though, provides some initial evidence of beneficial effects on the heart from a weight loss and exercise program. Participants used the Mediterranean diet plus an exercise program. Before the study, and at 12 and 24 months, they were examined using echocardiograms , electrocardiography , Holter monitor , CPET , cardiac MRI , and some blood tests. Participants also were given questionnaires asking how well they followed the diet and exercise protocols.

Not surprisingly, some participants lost a lot of weight while others lost less. Regardless of how much they lost, though, there was a significant pattern: the more weight lost, the better the results were for a reduction in several measurements related to the risk of developing atrial fibrillation, increasing their ability to exercise, and in the pressure in the pulmonary artery.

This small pilot study will hopefully lead to more extensive research. But in any case, it should help give us some of the motivation we need to lose some of that extra weight!

Source: Heart Failure Clinics , 17: 303-313. doi://10.1016/j.hfc.2021.01.003

Many readers may not be able to access this article without paying a fee. Some of the authors also published a popular article about this research.

HCMA Blog

By Sabrina Cuddy August 1, 2025
On a background of pink
By Julie Russo July 31, 2025
Sixty years ago, Medicaid and Medicare were established when President Lyndon B. Johnson signed the Social Security Amendments into law. The programs were a larger part of Johnson's "War on Poverty" agenda to combat inequality. Sixty years later, Medicaid and Medicare are under attack in ways that we could never have imagined. With the passage of the One Big Beautiful Bill Act (OBBBA), $1 trillion was cut from Medicaid and Medicare―the largest health care cut in U.S. history. As a result of the budget package, more than 15 million people will lose health insurance, hundreds of rural hospitals will close, and approximately 51,000 people will die preventable deaths each year. Congress voted for this harm, and Congress can fix it. We need them to invest in Medicaid and Medicare in order to undo this damage. Click here to send a message to Congress telling them to invest in these critical programs, not cut them. OBBBA is the exact opposite of the "War on Poverty." The bill was passed with brutal cuts to health care to fund more tax handouts for the very wealthy. It took from the poor to give to the rich. The unpopularity of these cuts cannot be overstated. Eighty-three percent of the American public, including three in four Republicans, has a favorable view of Medicaid. Congress must hear from us loud and clear: reverse course, undo the harm to Medicaid and Medicare, and protect health care for more than 71 million people. Join us in sending the message to Congress to invest in these critical programs, don't cut them. 1 The Truth About the One Big Beautiful Bill Act’s Cuts to Medicaid and Medicare 2 Research Memo: Projected Mortality Impacts of the Budget Reconciliation Bill 3 Medicaid keeps getting more popular as Republicans aim to cut it by $800 billion
By Lisa Salberg July 3, 2025
Summer, greetings to all our big-hearted friends As July approaches, our focus is already on the fall and preparing for some major events, including our annual meeting coming up in October. July will also find us on the west coast in Seattle conducting a regional patient education meeting as part of our big-hearted warrior tour. We have been following the generic drug quality issue in the United States very closely and encourage you to watch the series starting with our Hill briefing in April and following with the additional webinars with our partners at Medshadow and the People's Pharmacy, and of course the ProPublica series of articles. See them all here . We are happy to have a new team member on board - we welcome Pam as our coordinator of both our All Hearts Collaborative and Hearts and Minds project. Over the next few months, you're going to be learning more about these two amazing initiatives and how we are working to provide better services for big hearts regardless of where you live, so we are meeting all of our big-hearted friends where they are. Please stay tuned for updates from these projects coming soon. We are also creating new volunteer opportunities and engagements that we hope will make it easier for you to participate in spreading the message of the importance of diagnosis, the importance of community readiness related to CPR and AED use and, of course, helping patients get to their ultimate diagnosis and getting them on the proper treatment pathways. This July I would like to recognize all of the special birthdays in my family, including HCMA Center of Excellence coordinator, Stacey Titus-brown and my daughter Rebecca Salberg. It's a milestone birthday for Becca - it’s hard to believe I have a 30-year-old child. Wishing you all a happy and healthy summer. Go build some memories!
More Posts