Gordon Fox • November 24, 2021
Thanksgiving and gratitude

It’s Thanksgiving in the U.S. But we’re not going to list things we should be thankful for, or rehash the history of the holiday. Instead, let’s think about gratitude, a response to some benefit given to you by someone (or something) else.

Mental attitudes have been shown to affect our health. And this seems to be true for HCM as well. But let’s be clear: you won’t cure your heart by having a “positive attitude.” Many of us with HCM have stories about how infuriating it can be to have people tell us that we need to be more optimistic instead of having  (a myectomy, ICD, transplant, drug . . .). That said, attitude does matter.

There’s an old idea that the mind is entirely separate from the body. This is often called “Cartesian mind-body dualism” after the 17th century French philosopher René Descartes. Some people still think this. But research has shown that our minds are functions of our bodies, and that our state of mind can affect our bodies. By the way, let’s give Descartes credit. His work laid the basis for a lot of mathematics, scientific methodology, and philosophy. He wasn’t just some guy who thought odd stuff. But even really smart guys sometimes get things wrong.

Health and gratitude

There’s a fair bit of research on how gratitude affects health. It’s difficult to distinguish between people’s personalities (some people are just more likely to be grateful than others) and their responses to individual events. Researchers call the personality trait “trait gratitude,” and the responses to individual events “state gratitude.”

Gallagher et al. (2020) studied the effect of gratitude on healthy university students’ cardiovascular responses to stress. The stress was a repetitive arithmetic problem. Students were told they were not doing well, even when they were! Then they were told to repeat portions of the problem. The researchers asked if this affected blood pressure or heart rate. They scored gratitude with questionnaires: one about attitudes in life, and one about responses to events in the past week.

The result is impressive. The more students scored for state gratitude, the less their systolic blood pressure increased! There was no effect of trait gratitude. But neither measure of gratitude was related to changes in heart rate or diastolic pressure. The researchers controlled for a number of things that might confound the results.

This suggests that gratitude about recent life events may help people handle stress better.

What should we conclude about our own lives?

Our blood pressure may benefit from giving a bit of thought – and gratitude – to good things as they happen in life. That’s even relatively easy to do! I think it’s a bit comforting that there’s no suggestion in this study that we need to change our basic personalities. That’s hard to do!

We don’t know if gratitude may affect our cardiovascular health in other ways. We’ll have to wait for further research.

If we can ignore the tendency to eat and drink too much, Thanksgiving might actually offer some health benefits. Just remember to thank the cook!

Literature cited

S Gallagher, A. Castro Solano,  and M. Fernández Liporace. 2020. State, but not trait gratitude is associated with cardiovascular responses to acute psychological stress. Physiology & Behavior 221: 112896. https://doi.org/10.1016/j.physbeh.2020.112896

HCMA Blog

April 30, 2025
Medical Management means using medicines and other non-invasive therapies to relieve symptoms. It's exciting that new treatments for HCM are being studied and that the FDA approved Camzyos in 2022! HCM can cause various symptoms depending on how stiff the heart is, how much scarring (fibrosis) there is, and whether there is obstruction. Some people have no noticeable symptoms. Common symptoms are chest pain/pressure, shortness of breath, lightheadedness, fatigue, palpitations, and brain fog. Syncope (fainting) is dramatic but not as common as the other symptoms. Medications are the first-line treatment for symptoms of HCM. If patients can't take one class of medication, they can try a medication from a different class. Here are some medications used to treat HCM and what they're for: Beta Blockers - make your heart beat slower and relax better. They allow the heart to fill more completely between beats. They can lower blood pressure and relieve symptoms. Calcium Channel Blockers - used to lower blood pressure and slow the heart rate. May reduce symptoms from obstruction in HCM. Myosin Inhibitors - cause the heart to beat with less force. They may reduce obstruction and septal thickness in some patients. Camzyos (mavacamten) is the first of this class of medication. For more information, click HERE . Antiarrhythmics - help to restore normal rhythm in the heart. Blood Thinners - anticoagulants and anti-platelets make it harder for blood to clot. They are prescribed to reduce the risk of stroke. This risk is higher in patients with afib, aflutter, and artificial heart valves. Diuretics , or "water pills," help the kidneys get rid of extra water and salt, reducing swelling in the body. Sodium Channel Blockers - may reduce gradient in obstructive HCM and can treat chest pain. Some also act as antiarrhythmics. Antibiotics - treat or prevent bacterial infections. In HCM, they may be given before dental work to prevent infective endocarditis. To learn more and see the side effects of these medications, click HERE .
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