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tommyboy68
03-26-2006, 11:38 AM
For the past several years I have taken Zebeta (Bisoprolol) to regulate my blood pressure. For many years my cardiologist said that the Zebeta was doing better and doing more than we could have ever imagined. Everything was cool, except that every year we had to increase the dose. We started at 2.5 mg per day and wound up as 5 mg twice a day, which he says is the max I can take.

About six weeks ago I had my yearly echo and follow up and he said that my gradient was higher and my blood pressure was too high. Since I was maxed out on Zebeta he added Verapamil to the mix.

When I started the Verapamil it was amazing. I was 100% symptom free for about 3 weeks and my blood pressure immediately went down to around 115/74. I was a happy camper.

Then one night while I was filling in driving truck I got incredibly lightheaded, could not get oriented, broke out in a cold sweat and felt cold and tingly all over. I thought I was in serious trouble.

I'm not the kind of guy that ever calls for help, but that night was the exception. I called my wife and said "I think you better get me some help out here, like an EMT or something. Here's where I am." I kept her on the phone and it gradually subsided, so we didn't go to the hospital, I had her come pick me up and take me home.

I followed up with my cardiologist and he said maybe my heart rate was too low, so he cut the Zebeta to 7.5 mg per day and left the Verapamil at 120 mg per day. Now I'm back to having more symptoms than I've had in years.

Are Beta Blockers and CC Blockers not a good combination? I was on Atenolol in the beginning, but it was bringing back symptoms of Athsma I had as a child, so we switched to the Zebeta.

I'm looking for some talking points when I go for my next Cardiologist visit tomorrow morning and need some more ammunition in my arsenal of knowledge. :)

Reenie
03-26-2006, 02:15 PM
Many people are able to tolerate both beta and calcium channel blockers together, but not everyone can. It might help to switch to a different ccb. I don't know how much your cardiologist knows about HCM, but it's typical that many don't really understand it. Try to get that appointment with Mayo soon and see what the specialists have to say about your situation.

Reenie

BigHeart
03-28-2006, 10:54 PM
I also take bisoporol (Monocor) as it is very selective and therefore tolerated better by asthmatics. A regular cardiologist put me on Verapamil, as the old medical textbooks suggest its use. Verapamil only made my HOCM symptoms worse. My family doctor quickly took me off it.
When I went to a HCM specialist, he concured that verapamil was the wrong medication for my HOCM and put me on Norpace (Disopyramide Phosphate) - a potassium channel blocker. This combination of Norpace and bisoporol has worked well for me.

HuskerJeff
03-29-2006, 12:20 AM
I was on 180mg of Verapamil and 75mg of Toprol XL before my myectomy. My subjective opinion was that the Toprol was doing more for me than the Verapamil, but my local cardiologist thought the combination was best for me. I was on that combination for 2-3 months with mixed results - hence the surgery.

Since the myectomy (a little over 4 weeks ago), I've been on the Toprol only, as prescribed by my cardiologist at Mayo.